Research
Bladder Health Research Roundup: July 2026
Bladder health research in 2026: a new-class UTI antibiotic, an 82% bladder-cancer response, and the D-mannose trial that overturned popular UTI advice.
Research
Latest research and clinical studies on bladder conditions, treatments, and emerging therapies. Stay informed about advances in bladder health science.
The science behind bladder health is evolving. This section highlights recent and notable research, including clinical trials, emerging therapies, and new understandings of conditions like interstitial cystitis and recurrent UTIs. Topics range from the gut-bladder axis and fecal transplant studies to the link between anticholinergic medications and dementia risk. Each article summarises what researchers have found and what it may mean for patients.
15 items in Research
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MV140 UTI Vaccine: 54% Still UTI-Free at 9 Years
At year 9, 54% of MV140 UTI vaccine recipients were still UTI-free. The Phase 3 numbers, the access problem, and where the long-term data falls short.
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Phage Therapy for UTI: All 16 Patients Cleared in Phase 2
All 16 patients in the 2024 ELIMINATE Phase 2 trial cleared their UTI by day 10 with CRISPR-enhanced phage therapy. Here's what the Lancet data actually shows.
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Hyperbaric Oxygen for Radiation Cystitis: 14-Trial Review
RICH-ART RCT plus a 2024 meta-analysis of 14 trials (556 patients) puts hyperbaric oxygen for radiation cystitis at 90% improvement. Access is the harder part.
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Vitamin D Deficiency and Urinary Incontinence: Who Benefits
Vitamin D deficiency and urinary incontinence: women below 30 ng/mL have 45% higher risk. What blood levels protect bladder, when supplementing works.
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Methenamine Hippurate vs Antibiotics for Recurrent UTI
The 2022 ALTAR trial found methenamine hippurate non-inferior to daily antibiotic prophylaxis for preventing recurrent UTIs in women. Here's the evidence.
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Ketamine Bladder Syndrome: What the Research Shows
Latest research on ketamine bladder syndrome, how norketamine damages the bladder, new treatments like baclofen, and prevention for therapeutic users.
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The Urinary Microbiome: What Bladder Bacteria Mean
Your bladder isn't sterile. New research reveals how the urinary microbiome affects UTIs, overactive bladder, and interstitial cystitis treatment.
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Gene Therapy for Overactive Bladder: What Research Shows
New gene therapy for overactive bladder shows promising results in clinical trials. We review the URO-902 and EG110A data and what they mean for patients.
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Vitamin D and Bladder Health: What the Research Shows
Research links vitamin D deficiency to overactive bladder, urinary incontinence, and UTIs. Here's what the studies found and what it means for you.
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Probiotics for Bladder Health: What Research Shows
Evidence-based guide to probiotics for bladder health, covering UTI prevention, overactive bladder, strain recommendations, and what the research shows.
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Overactive Bladder Medication and Dementia Risk
What does the research say about overactive bladder medication and dementia risk? A look at which OAB drugs carry cognitive risks and safer alternatives.
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The Gut-Bladder Axis: How Gut Health Affects Your Bladder
New research reveals a gut-bladder axis linking your gut microbiome to UTIs, overactive bladder, and IC. Here's what the science says and what you can do.
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Fecal Transplant for Recurrent UTIs: What Research Shows
Can a fecal transplant prevent recurrent UTIs? We review the latest 2025 research on FMT for UTI prevention, including a reported 93% reduction in infections.
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Prof. Malone-Lee on chronic UTI: Why standard tests miss millions of infections
Prof. James Malone-Lee's research reveals why dipstick tests miss chronic UTIs and what this means for patients with persistent bladder symptoms.